Deadline: July 20, 2022

Application is open for the Developmental pathway funding scheme. You can apply for funding to develop and test novel therapeutics, medical devices, diagnostics, and other interventions.


You must be based at a research organization eligible for MRC funding.

Your project should focus on at least one of the following stages of development:

  • early development and design,
  • pre-clinical testing,
  • early-phase clinical studies and trials (up to phase 2a).

You should be based at an eligible research organization. These include:

  • higher education institutions
  • UKRI-approved independent research organizations or NHS bodies
  • government-funded organizations
  • MRC institutes
  • MRC units and partnership institutes
  • institutes and units funded by other research councils
  • public sector research establishments.

For more details on institutional and individual eligibility, see the MRC guidance for applicants.


Total fund: £30,000,000

There’s no limit on the amount of funding you can apply for. We will typically fund 80% of the full economic cost. This is an ongoing scheme with a budget of approximately £30 million a year. Application rounds open three times a year, in February, June, and October. This scheme was established in 2008 and is run by MRC. It is a key part of the MRC translational research strategy and supports the translation of fundamental discovery into benefits to human health.

Supporting documents

Outline case for support form (DOCX, 271KB)

Guidance for outline stage applicants (PDF, 228KB)

MRC guidance for applicants

Application process

You must first submit an outline proposal using the Joint Electronic Submission (Je-S) system.

When applying, select:

  • council: MRC
  • document type: outline proposal
  • scheme: Biomedical catalyst DPFS outline
  • call/type/mode: Developmental Pathway Funding Scheme (DPFS) outline July 2022.

You can find advice on completing your application in the Je-S handbook.

You must use our outline case for support form (DOCX, 271KB) for your Je-S application. Please read our guidance for outline stage applicants (PDF, 228KB) before applying.

If successful at the outline stage, you will be invited to submit a full application. We will send you guidance on completing a full application at this next stage.

The minimum time from outline submission to full decision is approximately 26 weeks. However, applicants can choose to defer their full submission by one round which would add approximately 16 weeks.

Click Here To Apply

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